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FDA Recalls, Market Withdrawals and Safety Alerts

There are no alerts as of 6/19/18
7-17-18 NC Department of Health and Human Services, Division of Public Health
Increase in Hepatitis A Infections and Actions for NC Clinicians
In response to an increased number of cases of hepatitis A reported in the Charlotte area since April 2018, this memo from the NC Division of Public Health urges NC clinicians to take the described steps to protect high risk patients and mitigate the spread of illness.
6-18-18 NC Department of Health and Human Services, Division of Public Health
Following the diagnosis of measles in a patient in Wake County, this memo  to NC clinicians provides recommendations to rapidly identify additional cases and control the spread of infection.
6-11-18 NC Department of Health and Human Services, Division of Public Health
This provider memo and CDC Health Advisory contain background information and recommendations regarding life threatening coagulopathy problems associated with the use of synthetic cannabinoids.
Additional information:
  • Synthetic Cannabinoids: An Overview for Healthcare Providers


Questions? Please contact the Office of Environmental Epidemiology at 919-695-2662.



5-31-18 NC Department of Health and Human Services, Division of Public Health  (NCDPH)
This memo from NCDPH:
  • provides information on the status of the Ebola virus disease (EVD) outbreak in the Democratic Republic of Congo as of 5/29/18
  • describes CDC recommendations for travelers and healthcare providers
  • provides contact information for NCDPH Communicable Disease Branch for assistance (919-733-3419)
Additional resources:
4-5-18 Centers for Disease Control and Prevention (CDC)
From 10 March 2018 through 05 April 2018, 94 people have presented to Emergency Departments (89 in Illinois, 2 in Indiana, 1 in Maryland, 1 in Missouri, and 1 in Wisconsin) with serious unexplained bleeding. None of these patients were on anticoagulation therapy or reported exposure to rat poisons containing a long-acting anti-coagulant brodifacoum. However, their work-up and their response to treatment with fresh frozen plasma and high doses of vitamin K was consistent with long-acting vitamin K-dependent antagonist toxicity. Laboratory investigation confirms brodifacoum exposure in at least 18 patients. There are 2 fatalities—both in Illinois. Illinois public health epidemiologists interviewed 63 patients, and they all reported synthetic cannabinoids use. At least 3 synthetic cannabinoid product samples related to this outbreak have tested positive for brodifacoum. A working hypothesis is the synthetic cannabinoids were contaminated with brodifacoum. Read more in link above.
3-6-18 NC Department of Health and Human Services
North Carolina health officials are alerting the pubic to a recent increase in emergency department visits by people who reported using cannabidiol (CBD) oil or a similar product in electronic cigarettes and/or vaporiging pens. Read more using link above.
2-20-18 Centers for Disease Control and Prevention (CDC)
Twenty-eight people infected with the outbreak strain of Salmonella I 4,[5],12:b:- have been reported from 20 states.  Eleven hospitalizations have been reported; no deaths.  
CA- 3 cases
NC, OH, OK, OR, PA, UT- 2 cases each
AL, AZ, CO, FL, KS, KY, LA, MA, MI, ND, NY, SC, TN- 1 case each
  • At this time, CDC recommends that people not consume kratom in any form because it could be contaminated with Salmonella. 
    • CDC’s recommendation may change as more information becomes available.
    • Kratom is also known as Thang, Kakuam, Thom, Ketom, and Biak.
    • Kratom is a plant consumed for its stimulant effects and as an opioid substitute.
  • CDC, public health and regulatory officials in several states, and the U.S. Food and Drug Administration are investigating a multistate outbreak of Salmonella I 4,[5],12:b:- infections.
  • Epidemiologic evidence indicates that kratom is a likely source of this multistate outbreak.
    • Ill people in this outbreak report consuming kratom in pills, powder, or tea.
    • No common brands or suppliers of kratom products have been identified at this time.
    • Because no common source of Salmonella-contaminated kratom has been identified, CDC is recommending against consuming any kratom.
12-27-17  Centers for Disease Control and Prevention (CDC)
The CDC is providing: 1) a notice about increased influenza A (H3N2) activity and its clinical implications; 2) a summary of influenza antiviral drug treatment recommendations; 3) an update about approved treatment drugs and supply this season; and 4) background information for patients about influenza treatment.
11-3-17  NC Division of Public Health (NC DPH)
Multiple states are investigating outbreaks of hepatitis A that have occurred primarily in persons who are homeless, persons who use drugs, men who have sex with men (MSM) and their close, direct contacts. Since July 2016, nearly 1200 cases have been reported to the Centers for Disease Control and Prevention (CDC), including 826 hospitalizations and 37 deaths.
9-27-17 NC Division of Public Health (NC DPH)
The NC Division of Public health identified a significant increase in overdoses from heroin, fentanyl, and fentanyl analogues in August 2017. Given this increase as well as the continuing opioid epidemic, NC DPH is distributing this alert to provide information on this situation and ongoing guidance to clinicians treating patients with opioid overdose and related conditions.
1-31-18 NC Division of Public Health
Update on 2017-18 Influenza Season
This memo provides clinicians with updated epidemiologic information regarding the 2017-18 influenza season and reinforces important prevention and control measures for the remainder of the season.